PLATFORMS > DYNAGROW™
Our Dynagrow platform can serve as an invaluable tool as you further your research in examining cellular mechanics, ion channel activation kinetics, tissue engineering, and regenerative medicine.
Cell Activation
Dynagrow can be aligned with routine cell culture practice. There is no need to transfer cells or constructs from their culture vessel to specially designed units to apply the magnetic field. Instead, the instrument allows cells cultured in standard tissue culture vessels (6, 24, and 96 well plates) to be secured within designated slots for subsequent magnetic stimulation.
Precise
DynaGrow can precisely target and activate individual ion channels or surface receptors on specific cells within a culture.
Control
Dynagrow technology can manipulate and remotely control specific cellular components, providing clinicians and scientists with a powerful tool for investigating cell function and molecular signalling pathways. Dynagrow has also demonstrated success in influencing stem cell growth and differentiation characteristics.
Functional
The Dynagrow system has the potential to serve as an addition to your current procedures without a radical overhaul of your current operations - it is compact enough to work on a tabletop or fit inside your existing incubators.
Potential
Dynagrow can facilitate the investigations of cell mechanical properties, mechanosensitive ion channel signalling pathways, targeted activation of specific ion channels, and mechanical conditioning of cells for regenerative medicine.
Applications:
Cell Culture & Tissue Modelling
Dynagrow can be aligned with routine cell culture practice. There is no need to transfer cells or constructs from their culture vessel to specially designed units to apply the magnetic field. Instead, the instrument allows cells cultured in standard tissue culture vessels (6, 24, and 96 well plates) to be secured within designated slots for subsequent magnetic stimulation.
Many tissues need mechanical conditioning combined with biochemical cues to grow and develop. Mesenchymal Stem Cells (MSC), in particular, benefit from mechanical cues to direct differentiation into the bone, muscle, or connective tissues.
Dynagrow can provide fully configurable mechanical cues to stimulate the production of functional tissue matrices to allow the development and growth of both 2D and 3D in vitro models. Controllable magnetic forces can also create dynamic organoid models that better replicate in vivo tissues, for example, gut peristalsis.
The precision of the Dynagrow platform allows for specific cell types in a heterogeneous culture to be magnetically labelled, allowing you to control the growth and development of one cell type in a population, a major help in the development of accurate 2D and 3D in vitro models.
Picture of the inside of bioreactor
Staff working
